• Publications using Optotune's technology

Publications

Focus tunable lenses

Microscopy
Focus and depth of field tunable detection system for compact quantum sensors

K. Frye-Arndt, A. Wacker, P. Brunssen, T. Dralle, H. Ahlers, W. Herr, E. Rasel, Optics Express, Vol. 34, Issue 3, pp. 3691-3701 (2026). **doi:**10.1364/OE.582238

Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissues

A. Glaser, J. Chandrashekar, S. Vasquez, C. Arshadi, N. Ouellette, X. Jiang, J. Baka, G. Kovacs, M. Woodard, S. Seshamani, K. Cao, N. Clack, A. Recknagel, A. Grim, P. Balaram, E. Turschak, M. Hooper, A. Liddell, J. Rohde, A. Hellevik, K. Takasaki, L. E. Barner, M. Logsdon, C. Chronopoulos, S. de Vries, J. Ting, S. Perlmutter, B. Kalmbach, N. Dembrow, B. Tasic, R C Reid, D Feng, K Svoboda, 2023 Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissueseLife12:RP91979, https://doi.org/10.7554/eLife.91979.2

Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for cleared samples

Vladimirov, N., Voigt, F.F., Naert, T. et al. Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for cleared samples. Nat Commun 15, 2679 (2024). https://doi.org/10.1038/s41467-024-46770-2

The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue

Voigt, F.F., Kirschenbaum, D., Platonova, E. et al. The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue. Nat Methods 16, 1105–1108 (2019). https://doi.org/10.1038/s41592-019-0554-0

Four-dimensional visualization of zebrafish cardiovascular and vessel dynamics by a structured illumination microscope with electrically tunable lens

Chen Chong, Li Simin, Wen Gang, Liang Yong, Wang Linbo, Yang Guang, Jin Xin, and Li Hui, Biomed. Opt. Express 11, 1203-1215 (2020) https://doi.org/10.1364/BOE.382114

High-speed color three-dimensional measurement based on parallel confocal detection with a focus tunable lens

Chang-Soo Kim, Wooseop Kim, Kyuhang Lee, and Hongki Yoo. Opt. Express, Vol. 27, No. 20/30 September 2019. https://doi.org/10.1364/OE.27.028466

Multi-plane, wide-field fluorescent microscopy for biodynamic imaging in vivo

Ruheng Shi, Cheng Jin, Hao Xie, Yuanlong Zhang, Xinyang Li, Qionghai Dai, and Lingjie Kong, Biomed. Opt. Express 10, 6625-6635 (2019). https://doi.org/10.1364/BOE.10.006625

Speeded-Up Focus Control of Electrically Tunable Lens by Sparse Optimization

Iwai, D., Izawa, H., Kashima, K. et al. Speeded-Up Focus Control of Electrically Tunable Lens by Sparse Optimization. Sci Rep 9, 12365 (2019). https://doi.org/10.1038/s41598-019-48900-z

Large depth-of-field 3D shape measurement using an electrically tunable lens

Xiaowei Hu, Guijin Wang, Yujin Zhang, Huazhong Yang, and Song Zhang, Opt. Express 27, 29697-29709 (2019) https://doi.org/10.1364/OE.27.029697

Experimental validations of a tunable-lens-based visual demonstrator of multifocal corrections

Vyas Akondi, Lucie Sawides, Yassine Marrakchi, Enrique Gambra, Susana Marcos, and Carlos Dorronsoro, Biomed. Opt. Express 9, 6302-6317 (2018) https://doi.org/10.1364/BOE.9.006302

Cell mechanotransduction with piconewton forces applied by optical tweezers

Fabio Falleroni, Vincent Torre, Dan Cojoc, Frontiers in cellular nanoscience (2018), https://doi.org/10.3389/fncel.2018.00130

Design and analysis of an 8x four-group zoom system using focus tunable lenses

Sun-Hyung Jo, Sung-Chan Park, Optics Express Vol.26, Issue 10, pp. 13370-13382 (2018), https://doi.org/10.1364/OE.26.013370

All-optical microscope autofocus based on an electrically tunable lens and a totally internally reflected IR laser

M. Bathe-Peters, P. Annibale, and M. J. Lohse, Optics Express Vol. 26, Issue 3, pp. 2359-2368 (2018), https://doi.org/10.1364/OE.26.002359

Three-dimensional Two-photon Optogenetics and Imaging of Neural Circuits in vivo

B. W. Yang, L. Carrillo-Reid, Y. Bando, D.S. Peterka, R. Yuste, bioRxiv preprint (2017). https://doi.org/10.1101/132506

NeuBtracker—imaging neurobehavioral dynamics in freely behaving fish

B. P. Symvoulidis, A. Lauri, A. Stefanoiu, M. Cappetta, S. Schneider, H. Jia, A. Stelzl, M. Koch, C. C. Perez, A. Myklatun, S. Renninger, A. Chmyrov, T. Lasser, W. Wurst, V. Ntziachristos, G. G. Westmeyer, Nature Methods – Brief communication (2017). doi:10.1038/nmeth.4459

High-speed dual-layer scanning photoacoustic microscopy using focus tunable lens modulation at resonant frequency

B. K. Lee, E. Chung, S. Lee, T. J. Eom, Optics Express, Vol 22, pp. 26427 (2017). doi.org/10.1364/OE.25.026427

Quantifying three-dimensional rodent retina vascular development using optical tissue clearing and light-sheet microscopy

B. J. N. Singh, T. M. Nowlin, G. J. Seedorf, S. H. Abman, D. P. Shepherd, J. Biomed. Opt., Vol 22, Issue 7, (7), pp. 2035-2046 (2011). doi:10.1117/1.JBO.22.7.076011

Three-dimensional multiple-particle tracking with nanometric precision over tunable axial ranges

B. G. Sancataldo, L. Scipioni, T. Ravasenga, L. Lanzanò, A. Diaspro, A. Barberis, and M. Duocastella, Optica Vol. 4, Issue 3, pp. 367-373 (2017)

Reduction of coherent artefacts in super-resolution fluorescence localisation microscopy

A. P. Georgiades, V. J. Allan, M. Dickinson, T. A. Waight, Journal of Microscopy (2016); doi: 10.1111/jmi.12453

High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes

Y. Nakai, M. Ozeki, T. Hiraiwa, R. Tanimoto, A. Funahashi, N. Hiroi, A. Taniguchi, S. Nonaka, V. Boilot, R. Shrestha, J. Clark, N. Tamura, V. M. Draviam and H. Oku, Rev. Sci. Instrum. 86, 013707 (2015)

Multi-depth photoacoustic microscopy with a focus tunable lens

Kiri Lee, Euiheon Chung, Tae Joong Eom, Proc. of SPIE Vol. 9323 93233O-1 (2015)

Calcium transient prevalence across the dendritic arbour predicts place field properties

M. E. J. Sheffield, D. A. Dombeck, Nature 517, 200–204 (2015)

3d high- and superresolution imaging using single-objective SPIM

Remi Galland et al., Nature Methods 3402, 1-4 (2015)

Fast imaging of live organisms with sculpted light sheets

A. K. Chmielewski, A. Kyrsting, P. Mahou, M. T. Wayland, L. Muresan, J. F. Evers & C. F. Kaminski, Scientific Reports 5, Article number: 9385 doi:10.1038/srep09385 (2015)

A rapid image acquisition method for focus stacking in microscopy

D. Clark, B. Brown, Microscopy Today, Volume 23, Issue 04, pp 18-25 (2015)

Rapid quantitative phase imaging for partially coherent light microscopy

B. José A. Rodrigo and Tatiana Alieva, Optics Express, Vol. 22, Issue 11, pp. 13472-13483 (2014)

Investigation of diffraction-based measurement errors in optical testing of aspheric optics with digital micromirror devices

Stephan Stuerwald, Robert Schmitt, J. Micro/Nanolith. MEMS MOEMS 13(1), 1-8, (2014)

Improved quantitative phase contrast in self-interference digital holographic microscopy and sensing dynamic refractive index changes of the cytoplasm using internalized microspheres as probes

B. Kemper, R. Schubert, S. Dartmann, A. Vollmer, S. Ketelhut, G. von Bally, SPIE Three Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XX, Proceedings Vol. 8589 (2013)

Rapid 3D light-sheet microscopy with a tunable lens

F. O. Fahrbach, F. F. Voigt, B. Schmid, F. Helmchen, J. Huisken, Optics Express, Vol. 21, Issue 18, pp. 21010-21026 (2013)

High-speed transport-of-intensity phase microscopy with an electrically tunable lens

C. Zuo, Q. Chen, W. Qu, and A. Asundi, Optics Express, Vol. 21, Issue 20, pp. 24060-24075 (2013)

Notch spatial filtering of image artifacts for structured illumination microscopy of cell-based assays

Jong-ryul Choi, Donghyun Kim, Optics Communications 308 (2013) 142–146 (2013)

Fast two-layer two-photon imaging of neuronal cell populations using an electrically tunable lens

B. F. Grewe, F. F. Voigt, M. van’t Hoff, F. Helmchen, Biomedical Optics Express, Vol. 2, Issue 7, pp. 2035-2046 (2011)

Optical Coherence Tomography (OCT)
Swept source optical coherence tomography and tunable lens technology for comprehensive imaging and biometry of the whole eye

I. Grulkowski, S. Manzanera, L. Cwiklinski, F. Sobczuk, K. Karnowski, and Pablo Artal, Optica, Vol. 5, Issue 1, p.52-59 (2018)

Microscope-integrated intraoperative OCT with electrically tunable focus and heads-up display for imaging of ophthalmic surgical maneuvers

B. Y. K. Tao, S. K. Srivastava, J. P. Ehlers, Biomedical Optics Express, Vol. 5, Issue 6, pp. 1877-1885 (2014).

Space applications
Miniature Optical Steerable Antenna for Intersatellite Communications Liquid Lens Characterization

F. Fogle, O. Cierny, P. V. Pereira, W. Kammerer, K. Cahoy, 2020 IEEE Aerospace Conference (2020)

Optical Performance of Commercial Liquid Lens Assemblies in Microgravity

S. Kacher, K. Cahoy, Optical Engineering, Vol. 62, Issue 11, 113106 (2023)

Other applications
Instrument for fast whole-field peripheral refraction in the human eye

E. J. Fernandez, S. Sager, Z. Lin, J. Hao, J. Roca, P. M. Prieto, Z. Yang, W. Lan, and P. Artal, Biomedical Optics Express 13, pp. 2947-2959 (2022)

Design and characterisation of terabit/s capable compact localisation and beam-steering terminals for fiber-wireless-fiber links

Singh, Ravinder, et al. Journal of Lightwave Technology 38.24, 6817-6826 (2020)

Synthetic three-dimensional atomic structures assembled atom by atom

D. Barredo, V. Lienhard, S. de Léséleuc, Th. Lahaye, and A. Browaeys, arXiv:1712.02727 [quant-ph] (2017)

Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery

D. Volpi, I. D. C. Tullis, P. R. Barber, E. M. Augustyniak, S. C. Smart, K. A. Vallis, and B. Vojnovic, Biomedical Optics Express Vol. 8, Issue 7, pp. 3232-3247 (2017)

Optimizing virtual reality for all users through gaze-contingent and adaptive focus displays

N.Padmanaban, R. Konrad, T. Stramer, E. A. Cooper, G. Wetzstein, PNAS (2017)

Novel Optical Configurations for Virtual Reality: Evaluating User Preference and Performance with Focus-tunable and Monovision Near-eye Displays

R. Konrad, E. A. Cooper, G. Wetzstein, (2016)

Dynamic lens and monovision 3D displays to improve viewer comfort

P. V. Johnson, J. A.Q. Parnell, J. Kim, C. D. Saunter, G. D. Love, M. S. Banks, arXiv:1512.09163 (2015)

Optical transport of ultracold atoms using focus-tunable lenses

J. Léonard, M. Lee, A. Morales, T. Karg, T. Esslinger, T. Donner, New J. Phys. 16093028 (2014)

Spherical refractive correction with an electro-optical liquid lens in a double-pass system

P. F. Sanabria, F. Diaz-Douton, M. Aldaba, J Pujol, J. Europ. Opt. Soc. Rap. Public. 8,13062 (2013)

Measurement of the M2 beam propagation factor using a focus-tunable liquid lens

R. D. Niederriter, J. T. Gopinath, M. E. Siemens, Applied Optics, Vol. 52, Issue 8, pp. 1591-1598 (2013)

Focal Sweep Videography with Deformable Optics

D. Miau, O. Cossairt, and S. K. Nayar, IEEE International Conference on Computational Photography (ICCP) (2013)

Simulation and realization of a focus shifting unit using a tunable lens for 3D laser material processing

G. Eberle, V. Chiron, K. Wegener,  Lasers in Manufacturing Conference, Munich, Germany (2013)

Laser speckle reduction

Microscopy
Reduction of coherent artefacts in super-resolution fluorescence localisation microscopy

P. Georgiades, V. J. Allan, M. Dickinson, and T. A. Waight, Journal of Microscopy, 264: 375–383, doi:10.1111/jmi.12453 (2016).